Article
Global profiles of gene expression induced by adrenocorticotropin in Y1 mouse adrenal cells.
Endocrinology - 1 May 2006
Schimmer Bernard P, Cordova Martha, Cheng Henry, Tsao Andrew, Goryachev Andrew B, Schimmer Aaron D, Morris Quaid
Abstract excerpt
ACTH regulates the steroidogenic capacity, size, and structural integrity of the adrenal cortex through a series of actions involving changes in gene expression; however, only a limited number of ACTH-regulated genes have been identified, and these only partly account for the global effects of ACTH on the adrenal cortex. In this study, a National Institute on Aging 15K mouse cDNA microarray was used to identify...
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