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Article

Impact of ACTH Signaling on Transcriptional Regulation of Steroidogenic Genes

29 Mar 2016

Abstract excerpt

The trophic peptide hormone adrenocorticotropic (ACTH) stimulates steroid hormone biosynthesis evoking both a rapid, acute response and a long-term, chronic response, via the activation of cAMP/protein kinase A (PKA) signaling. The acute response is initiated by the mobilization of cholesterol from lipid stores and its delivery to the inner mitochondrial membrane, a process that is mediated by the steroidogenic...

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Identifiers

PMID: 27065945
DOI: 10.3389/fendo.2016.00024

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Impact of ACTH Signaling on Transcriptional Regulation of Steroidogenic GenesPMID 27065945Read ↗

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