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Article

ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex

20 May 2003

Abstract excerpt

Steroid hormone biosynthesis in the adrenal cortex and gonads involves the coordinated transcription of the genes encoding the steroid hydroxylases, 3beta-hydroxysteroid dehydrogenase (3betaHSD), the steroidogenic acute regulatory protein (StAR), and adrenodoxin (Adx). Transcriptional regulation of steroidogenic genes is multifactorial, entailing developmental, tissue-specific, constitutive, and cAMP-dependent...

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Identifiers

PMID: 12768545
DOI: 10.1002/jemt.10339

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