Article
Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathologic development of oral cancer.
Head & neck - 1 Mar 2012
Chien Ming-Hsien, Chou Lin Shih-Shen, Chung Tsung-Te, Lin Chien-Huang, Chou Ming-Yung, Weng Meng-Shih, Yang Shun-Fa, Chen Mu-Kuan
Abstract excerpt
BACKGROUND: This study investigates the association between polymorphism in the E-cadherin/CDH1 promoter region and the risk and progression of oral cancer. METHODS: Genetic polymorphisms of CDH1-160 and -347 were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 347 noncancer controls and in 251 patients with oral cancer. RESULTS: The statistical analysis showed that...
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