Article
The Associations of Genetic Variants in E-cadherin Gene With Clinical Outcome of Epithelial Ovarian Cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Nov 2016
Juan Wang, Shan Kang, Na Wang, Rong-Miao Zhou, Yan Li
Abstract excerpt
OBJECTIVE: The E-cadherin protein plays major roles in tumor progression, invasion, and metastasis. Polymorphisms located in the E-cadherin gene (CDH1) may contribute to increased risks of specific cancers. In this study, we evaluated the associations between genetic variants in CDH1 and the clinical outcomes of patients with epithelial ovarian cancer (EOC). MATERIALS AND METHODS: We assessed the -160C/A and...
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