Article
Family-based association analysis implicates IL-4 in susceptibility to Kawasaki disease.
Genes and immunity - 1 Aug 2005
Burns J C, Shimizu C, Shike H, Newburger J W, Sundel R P, Baker A L, Matsubara T, Ishikawa Y, Brophy V A, Cheng S, Grow M A, Steiner L L, Kono N, Cantor R M
Abstract excerpt
Several compelling lines of evidence suggest an important influence of genetic variation in susceptibility to Kawasaki disease (KD), an acute vasculitis that causes coronary artery aneurysms in children. We performed a family-based genotyping study to test for association between KD and 58 genes involved in cardiovascular disease and inflammation. By analysis of a cohort of 209 KD trios using the transmission...
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