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Article

Genetic variations in the receptor-ligand pair CCR5 and CCL3L1 are important determinants of susceptibility to Kawasaki disease.

The Journal of infectious diseases - 15 Jul 2005

Burns Jane C, Shimizu Chisato, Gonzalez Enrique, Kulkarni Hemant, Patel Sukeshi, Shike Hiroko, Sundel Robert S, Newburger Jane W, Ahuja Sunil K

Abstract excerpt

Kawasaki disease (KD) is an enigmatic, self-limited vasculitis of childhood that is complicated by development of coronary-artery aneurysms. The high incidence of KD in Asian versus European populations prompted a search for genetic polymorphisms that are differentially distributed among these populations and that influence KD susceptibility. Here, we demonstrate a striking, inverse relationship between the...

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Identifiers

PMID: 15962231
DOI: 10.1086/430953
PMCID: PMC2894631

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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