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Article

Pharmacogenomics of coronary artery response to intravenous gamma globulin in kawasaki disease

30 May 2024

Abstract excerpt

Kawasaki disease (KD) is a multisystem inflammatory illness of infants and young children that can result in acute vasculitis. The mechanism of coronary artery aneurysms (CAA) in KD despite intravenous gamma globulin (IVIG) treatment is not known. We performed a Whole Genome Sequencing (WGS) association analysis in a racially diverse cohort of KD patients treated with IVIG, both using AHA guidelines. We defined...

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PMID: 38816462
DOI: 10.1038/s41525-024-00419-7

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