Enhanced sodium-dependent extrusion of magnesium in mutant cells established from a mouse renal tubular cell line.

Abstract excerpt

To study the regulatory mechanisms of intracellular Mg(2+) concentration ([Mg(2+)](i)) in renal tubular cells as well as in other cell types, we established a mutant strain of mouse renal cortical tubular cells that can grow in culture media with very high extracellular Mg(2+) concentrations ([Mg(2+)](o) > 100 mM: 101Mg-tolerant cells). [Mg(2+)](i) was measured with a fluorescent indicator furaptra (mag-fura 2)...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antiporters
• Share to Culture Media