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Article

Increased Na(+)-H+ antiporter activity in apical membrane vesicles from mutant LLC-PK1 cells.

The American journal of physiology - 1 Apr 1991

Reilly R F, Haggerty J G, Aronson P S, Adelberg E A, Slayman C W

Abstract excerpt

In whole cell experiments, the PKE20 mutant of the renal epithelial cell line LLC-PK1 displays a severalfold elevation of Na(+)-H+ antiporter activity at the apical surface (J.G. Haggerty, N. Agarwal, R.F. Reilly, E. A. Adelberg, and C.W. Slayman. Proc. Natl. Acad. Sci. USA 85: 6797-6801, 1988). The present study was undertaken to explore the properties of the mutant at the membrane level. Apical membrane...

Topics

Amiloride
Animals
Carrier Proteins
Cell Fractionation
Cell Line
Cell Membrane
Clone Cells
Electrophoresis, Polyacrylamide Gel
Kinetics
Membrane Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sodium

Sodium-Hydrogen Exchangers

Sodium-Potassium-Exchanging ATPase

gamma-Glutamyltransferase

Source

Identifiers

PMID: 1673319
DOI: 10.1152/ajpcell.1991.260.4.C738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1673319-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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