Article
RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination.
The Journal of biological chemistry - 29 Jul 2005
Doherty Kevin M, Sharma Sudha, Uzdilla Laura A, Wilson Teresa M, Cui Sheng, Vindigni Alessandro, Brosh Robert M
Abstract excerpt
Understanding the molecular and cellular functions of RecQ helicases has attracted considerable interest since several human diseases characterized by premature aging and/or cancer have been genetically linked to mutations in genes of the RecQ family. Although a human disease has not yet been genetically linked to a mutation in RECQ1, the prominent roles of RecQ helicases in the maintenance of genome stability...
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