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Article

Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.

Proceedings of the National Academy of Sciences of the United States of America - 17 May 2005

Chen Min, Gavrilova Oksana, Liu Jie, Xie Tao, Deng Chuxia, Nguyen Annie T, Nackers Lisa M, Lorenzo Javier, Shen Laura, Weinstein Lee S

Abstract excerpt

Gnas is an imprinted gene with multiple gene products resulting from alternative splicing of different first exons onto a common exon 2. These products include stimulatory G protein alpha-subunit (G(s)alpha), the G protein required for receptor-stimulated cAMP production; extralarge G(s)alpha (XLalphas), a paternally expressed G(s)alpha isoform; and neuroendocrine-specific protein (NESP55), a maternally expressed...

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Share to Blood Glucose
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Energy Metabolism

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Share to GTP-Binding Protein alpha Subunits, Gs

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Source

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Identifiers

PMID: 15883378
DOI: 10.1073/pnas.0408268102
PMCID: PMC1129092

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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