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Article

Increased insulin sensitivity in paternal Gnas knockout mice is associated with increased lipid clearance.

Endocrinology - 1 Sept 2004

Chen Min, Haluzik Martin, Wolf Nicole J, Lorenzo Javier, Dietz Kelly R, Reitman Marc L, Weinstein Lee S

Abstract excerpt

The G protein alpha-subunit Gsalpha is required for hormone-stimulated cAMP generation. The Gsalpha gene Gnas is a complex gene with multiple imprinted gene products. Mice with heterozygous disruption of the Gnas paternal allele (+/p-) are partially Gsalpha deficient and totally deficient in XLalphas, a neuroendocrine-specific Gsalpha isoform that is expressed only from the paternal Gnas allele. We previously...

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Source

Identifiers

PMID: 15166122
DOI: 10.1210/en.2004-0038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Increased insulin sensitivity in paternal Gnas knockout mice is associated with increased lipid clearance.PMID 15166122Read ↗

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