Article
Physiological dysfunctions associated with mutations of the imprinted Gnas locus.
Physiology (Bethesda, Md.) - 1 Aug 2008
Krechowec Stefan, Plagge Antonius
Abstract excerpt
The ubiquitous Galphas-subunit of the trimeric, stimulatory G-protein plays a central role in receptor-mediated signal transduction, coupling receptor activation with the production of cAMP. The Galphas-encoding locus Gnas is now known to consist of a complex arrangement of several protein-coding...
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