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Article

Reduced expression of the PTH/PTHrP receptor during development of the mammary gland influences the function of the nipple during lactation.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2005

Kobayashi Tatsuya, Kronenberg Henry M, Foley John

Abstract excerpt

Signaling by the parathyroid hormone/parathyroid hormone-related protein receptor (Ppr) is necessary for mammary gland development beyond the early induction stage in mice. We used a series of murine models of reduced Ppr expression to determine how diminished receptor signaling influences mammary development. Reduction of Ppr expression to very low levels prevented mammary gland development. A less-severe...

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Share to Gene Expression Regulation, Developmental
Share to Lactation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammary Glands, Animal

Share to Matrix Metalloproteinase 2

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Share to Models, Genetic

Share to Parathyroid Hormone-Related Protein

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Source

Identifiers

PMID: 15880431
DOI: 10.1002/dvdy.20406

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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