Article
Cytochrome P450c17alpha gene (CYP17) polymorphism is associated with serum estrogen and progesterone concentrations.
Cancer research - 15 Feb 1998
Feigelson H S, Shames L S, Pike M C, Coetzee G A, Stanczyk F Z, Henderson B E
Abstract excerpt
An increased level of serum estrogen is one marker of breast cancer risk. We have recently reported that increased risk of advanced breast cancer is associated with a common allele of the cytochrome P450c17alpha gene (CYP17), designated A2. We now show that CYP17 genotype is associated with serum hormone levels among 83 young, nulliparous women. Serum estradiol (E2) levels measured around day 11 of the menstrual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.