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Article

In vivo excision of a single targeted nucleotide from an mRNA by a trans excision-splicing ribozyme.

RNA (New York, N.Y.) - 1 Jun 2005

Baum Dana A, Testa Stephen M

Abstract excerpt

We have previously reported the development of a group I intron-derived ribozyme that can bind an exogenous RNA substrate and excise from that substrate an internal segment in vitro, which allows for sequence-specific modification of RNA molecules. In this report, the activity of this trans excision-splicing ribozyme in a cellular environment, specifically Escherichia coli, was investigated. The ribozyme was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15872183
DOI: 10.1261/rna.2050505
PMCID: PMC1370774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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