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Article

Polymorphisms in the IL-12B gene and outcome of HCV infection.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 May 2005

Houldsworth Annwyne, Metzner Magdalena, Rossol Siegbert, Shaw Steve, Kaminski Edward, Demaine Andy G, Cramp Matthew E

Abstract excerpt

Most people with hepatitis C virus (HCV) develop chronic infection with persistent viremia. Resolution of infection is associated with antiviral cellular immune responses of T helper 1 (Th1) type. Interleukin-12 (IL-12) is a key cytokine in the generation of Th1 responses, and functionally relevant polymorphisms of the IL12B gene and its promoter have been described recently. We sought an association between...

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Identifiers

PMID: 15871664
DOI: 10.1089/jir.2005.25.271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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