Article
Interleukin 12B gene polymorphism and apparent resistance to hepatitis C virus infection.
Clinical and experimental immunology - 1 Jun 2008
Hegazy D, Thurairajah P, Metzner M, Houldsworth A, Shaw S, Kaminski E, Demaine A G, Cramp M E
Abstract excerpt
Cellular immunity with interferon gamma production could have a role in protection from hepatitis C virus (HCV). Interleukin (IL)-12 is a key cytokine in promoting such anti-viral T helper 1 (Th1) responses. We hypothesized that a genetic background able to promote cellular responses may be associated with apparent protection from infection and have investigated the distribution of the functional 1188A/C...
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