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Article

Characterization of fluoroquinolone and carbapenem susceptibilities in clinical isolates of levofloxacin-resistant Pseudomonas aeruginosa.

Chemotherapy - 1 May 2005

Muramatsu Hideaki, Horii Toshinobu, Takeshita Akihiro, Hashimoto Hisakuni, Maekawa Masato

Abstract excerpt

BACKGROUND: Pseudomonas aeruginosa can rapidly acquire resistance to antibiotics, including fluoroquinolones and carbapenems. METHODS: We characterized fluoroquinolone, carbapenem and other beta-lactam susceptibilities and analyzed fluoroquinolone and carbapenem resistance in 16 clinical isolates of levofloxacin-resistant P. aeruginosa. RESULTS: All levofloxacin-resistant isolates showed high MICs (> or =32...

Topics

Anti-Bacterial Agents
Carbapenems
DNA Gyrase
DNA Topoisomerase IV
Drug Resistance, Bacterial
Fluoroquinolones
Humans
Levofloxacin
Microbial Sensitivity Tests
Mutation
Ofloxacin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Porins

Pseudomonas Infections

Pseudomonas aeruginosa

Source

Identifiers

PMID: 15870499
DOI: 10.1159/000085612

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