Article
In vitro selection of resistance in Pseudomonas aeruginosa and Acinetobacter spp. by levofloxacin and ciprofloxacin alone and in combination with beta-lactams and amikacin.
The Journal of antimicrobial chemotherapy - 1 Aug 2005
Drago Lorenzo, De Vecchi Elena, Nicola Lucia, Tocalli Loredana, Gismondo Maria Rita
Abstract excerpt
OBJECTIVES: The aim of this study was to evaluate the ability of levofloxacin and ciprofloxacin alone and in combination with either ceftazidime, cefepime, imipenem, piperacillin-tazobactam or amikacin to select for antibiotic-resistant mutants of Pseudomonas aeruginosa and Acinetobacter spp. METHODS: Clinical strains of P. aeruginosa (n = 5) and Acinetobacter spp. (n = 5) susceptible to all the drugs used in the...
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