Article
Phenotypic and genotypic analysis of levofloxacin-resistant clinical isolates of Streptococcus pneumoniae collected in 13 countries during 1999-2000.
International journal of antimicrobial agents - 1 Aug 2002
Critchley Ian A, Blosser-Middleton Renée S, Jones Mark E, Karlowsky James A, Karginova Elena A, Thornsberry Clyde, Sahm Daniel F
Abstract excerpt
During 1999-2000, 5015 isolates were collected from 13 countries and tested against levofloxacin. Overall, levofloxacin resistance minimum inhibitory concentration (MIC>or =8 mg/l) was found in 40 isolates (0.8%). The highest resistance rates were in Hong Kong (8.0%), China (3.3%) and Spain (1.6%). Levofloxacin retained an MIC(90) of 1 mg/l in all countries. Pulsed-field gel electrophoresis analysis of resistant...
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