Article
Phenotypic and genotypic analysis of levofloxacin-resistant clinical isolates of Streptococcus pneumoniae collected in 13 countries during 1999-2000.
International journal of antimicrobial agents - 1 Aug 2002
Critchley Ian A, Blosser-Middleton Renée S, Jones Mark E, Karlowsky James A, Karginova Elena A, Thornsberry Clyde, Sahm Daniel F
Abstract excerpt
During 1999-2000, 5015 isolates were collected from 13 countries and tested against levofloxacin. Overall, levofloxacin resistance minimum inhibitory concentration (MIC>or =8 mg/l) was found in 40 isolates (0.8%). The highest resistance rates were in Hong Kong (8.0%), China (3.3%) and Spain (1.6%...
Topics
- Anti-Infective Agents
- Asia
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Europe
- Genotype
- Humans
- Levofloxacin
- Mexico
- Microbial Sensitivity Tests
- Mutation
- Ofloxacin
- Phenotype