Article
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
The Journal of nutrition - 1 May 2005
Davis Steven R, Quinlivan Eoin P, Shelnutt Karla P, Ghandour Haifa, Capdevila Antonieta, Coats Bonnie S, Wagner Conrad, Shane Barry, Selhub Jacob, Bailey Lynn B, Shuster Jonathan J, Stacpoole Peter W, Gregory Jesse F
Abstract excerpt
The effects of folate status and the methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism on the kinetics of homocysteine metabolism are unclear. We measured the effects of dietary folate restriction on the kinetics of homocysteine remethylation and synthesis in healthy women (20-30 y old) with the MTHFR 677 C/C or T/T genotypes (n = 9/genotype) using i.v. primed, constant infusions of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.