Article
Polymorphisms of key enzymes in homocysteine metabolism affect diet responsiveness of plasma homocysteine in healthy women.
The Journal of nutrition - 1 Oct 2001
Silaste M L, Rantala M, Sämpi M, Alfthan G, Aro A, Kesäniemi Y A
Abstract excerpt
High plasma total homocysteine (tHcy), low dietary intake of folate and other B vitamins, and genetic polymorphisms related to metabolism of homocysteine may interactively contribute to the risk of cardiovascular disease. We investigated whether known mutations in genes regulating homocysteine metabolism affect the responsiveness of serum folate and plasma tHcy to high intake of natural folate from food. Healthy...
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