Article
Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression.
Archives of general psychiatry - 1 May 2005
Taylor Warren D, Steffens David C, Payne Martha E, MacFall James R, Marchuk Douglas A, Svenson Ingrid K, Krishnan K Ranga R
Abstract excerpt
CONTEXT: Polymorphisms in the promoter region of the serotonin transporter gene (5-HTTLPR) influence transcription and may play a role in the pathogenesis and course of depression. Recent research demonstrates that specific polymorphisms may be associated with differences in hippocampal volumes in subjects with depression. OBJECTIVE: To examine associations between 5-HTTLPR genotype and hippocampal volumes in...
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