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Article

No association between genetic polymorphisms in NAD(P)H oxidase p22phox and paraoxonase 1 and colorectal cancer risk.

Anticancer research - 1 Jan 2000

Van Der Logt Elise M J, Janssen Cynthia H J M, Van Hooijdonk Zairah, Roelofs Hennie M J, Wobbes Theo, Nagengast Fokko M, Peters Wilbert H M

Abstract excerpt

BACKGROUND: Impaired metabolism of ingested toxic or carcinogenic compounds is a postulated mechanism underlying colorectal cancer (CRC). Furthermore, it is suggested that reactive oxygen species (ROS) may play a role in human cancer development. Polymorphic variations in NAD(P)H oxidase p22phox and paraoxonase 1 (PON1) enzyme activities may alter superoxide production or the rate of chemical metabolism,...

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PMID: 15865106

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PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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