Article
Genetic polymorphism 609C>T in NAD(P)H:quinone oxidoreductase 1 enhances the risk of proximal colon cancer.
Journal of human genetics - 1 Jul 2014
Freriksen Jolien J M, Salomon Jody, Roelofs Hennie M J, Te Morsche Rene H M, van der Stappen Jos W J, Dura Polat, Witteman Ben J M, Lacko Martin, Peters Wilbert H M
Abstract excerpt
Gastrointestinal (GI) cancer is responsible for the majority of deaths among all types of cancer. Lifestyle factors may not only be the main risk factor for GI cancer but reactive oxygen species (ROS) may also be involved. The single-nucleotide polymorphisms (SNPs) 609C>T (rs1800566) and 465C>T (...
Topics
- Alleles
- Case-Control Studies
- Colonic Neoplasms
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- NAD(P)H Dehydrogenase (Quinone)