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Article

Genetic polymorphism 609C>T in NAD(P)H:quinone oxidoreductase 1 enhances the risk of proximal colon cancer.

Journal of human genetics - 1 Jul 2014

Freriksen Jolien J M, Salomon Jody, Roelofs Hennie M J, Te Morsche Rene H M, van der Stappen Jos W J, Dura Polat, Witteman Ben J M, Lacko Martin, Peters Wilbert H M

Abstract excerpt

Gastrointestinal (GI) cancer is responsible for the majority of deaths among all types of cancer. Lifestyle factors may not only be the main risk factor for GI cancer but reactive oxygen species (ROS) may also be involved. The single-nucleotide polymorphisms (SNPs) 609C>T (rs1800566) and 465C>T (rs1131341) in the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene lead to a decline in NQO1 enzyme activity. NQO1...

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Identifiers

PMID: 24830960
DOI: 10.1038/jhg.2014.38

Genes

NQO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic polymorphism 609C>T in NAD(P)H:quinone oxidoreductase 1 enhances the risk of proximal colon cancer.PMID 24830960Read ↗

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