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Article

The XPC poly-AT polymorphism in non-melanoma skin cancer.

Cancer letters - 26 May 2005

Nelson Heather H, Christensen Brock, Karagas Margaret R

Abstract excerpt

Signature UV-DNA lesions, cyclobutane dimers and 6-4 photoproducts, are repaired via the nucleotide excision repair pathway. NER may be subdivided into transcription-coupled repair and global genome repair, and the XPC protein is specific to this latter repair pathway recognizing helix distorting lesions and initiating their repair. Inactivating XPC mutations are associated with xeroderma pigmentosa and an...

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Source

Identifiers

PMID: 15863269
DOI: 10.1016/j.canlet.2004.11.032

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The XPC poly-AT polymorphism in non-melanoma skin cancer.PMID 15863269Read ↗

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A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism.Semantic proximity Read ↗

Polymorphisms in the DNA repair genes XPC, XPD, and XPG and risk of cutaneous melanoma: a case-control analysis.Semantic proximity Read ↗

Molecular genetic analysis of 16 XP-C patients from Germany: environmental factors predominately contribute to phenotype variations.Semantic proximity Read ↗

Poly (AT) Polymorphism in Intron 11 of the XPC DNA Repair Gene Enhances the Risk of Lung CancerSemantic proximity Read ↗

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Poly (AT) polymorphism in intron 11 of the XPC DNA repair gene enhances the risk of lung cancer.Semantic proximity Read ↗

Poly (AT) polymorphism in the XPC gene and smoking enhance the risk of prostate cancer in a low-risk Chinese population.Semantic proximity Read ↗

Poly (AT) deletion/insertion polymorphism of the XPC gene contributes to urinary system cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

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