Article
An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study.
Cancer research - 15 Apr 2001
Shen H, Sturgis E M, Khan S G, Qiao Y, Shahlavi T, Eicher S A, Xu Y, Wang X, Strom S S, Spitz M R, Kraemer K H, Wei Q
Abstract excerpt
Inherited polymorphisms of DNA repair genes may contribute to variations in DNA repair capacity and genetic susceptibility to cancer. In a hospital-based case-control study of 287 non-Hispanic white patients with newly diagnosed SCCHN and 311 control subjects matched on age, sex, ethnicity, and smoking status, we investigated the role of a newly identified variant allele of XPC, XPC-PAT+. We found that the...
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