Article
Poly (AT) polymorphism in the XPC gene and smoking enhance the risk of prostate cancer in a low-risk Chinese population.
Cancer genetics - 1 May 2012
Liu Yang, Chen Zhiwen, Wei Quanfang, Yuan Fang, Zhi Yi, Song Bo, Yang Jin
Abstract excerpt
We investigated two polymorphisms of xeroderma pigmentosum complementary group C (XPC) in 202 subjects with prostate cancer (PCa) and 221 healthy controls in a Chinese Han population. Genotyping was performed using a polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) technique. Our results indicated that smoking is associated with an increased risk for PCa (odds ratio [OR]: 1.51; 95%...
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