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Article

Assessment of 3 xeroderma pigmentosum group C gene polymorphisms and risk of cutaneous melanoma: a case-control study.

Carcinogenesis - 1 Jun 2005

Blankenburg Sandra, König Inke R, Moessner Rotraut, Laspe Petra, Thoms Kai-Martin, Krueger Ullrich, Khan Sikandar G, Westphal Goetz, Berking Carola, Volkenandt Matthias, Reich Kristian, Neumann Christine, Ziegler Andreas, Kraemer Kenneth H, Emmert Steffen

Abstract excerpt

Individuals with the rare DNA repair deficiency syndrome xeroderma pigmentosum (XP) are sensitive to the sun and exhibit a 1000-fold increased risk for developing skin cancers, including cutaneous melanoma. Inherited polymorphisms of XP genes may contribute to subtle variations in DNA repair capacity and genetic susceptibility to melanoma. We investigated the role of three polymorphic alleles of the DNA repair...

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Identifiers

PMID: 15731165
DOI: 10.1093/carcin/bgi055

Genes

XPC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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