Article
XPA, haplotypes, and risk of basal and squamous cell carcinoma.
Carcinogenesis - 1 Aug 2006
Miller Katie L, Karagas Margaret R, Kraft Peter, Hunter David J, Catalano Paul J, Byler Steven H, Nelson Heather H
Abstract excerpt
Nucleotide excision repair (NER) is instrumental in removing DNA lesions caused by ultraviolet (UV) radiation, the dominant risk factor for keratinocyte carcinoma, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). We evaluated whether BCC or SCC risk was influenced by the A23G single nucleotide polymorphism (SNP) in Xeroderma pigmentosum group A (XPA), which codes for an essential protein in...
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