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Article

11beta-Hydroxysteroid dehydrogenase in the heart of normotensive and hypertensive rats.

The Journal of steroid biochemistry and molecular biology - 1 Feb 2005

Mazancová Karla, Kopecký Martin, Miksík Ivan, Pácha Jirí

Abstract excerpt

Corticosteroids have been shown to play a role in cardiac remodeling, with the possibility of a direct effect of overexpression of 11beta-hydroxysteroid dehydrogenase (11HSD) isoform 2 at the level of the cardiomyocytes. The aim of this study was to examine cardiac steroid metabolism in hypertensive rats with hearts that are hypertrophied and fibrotic and have structural alterations in the coronary circulation....

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Identifiers

PMID: 15862976
DOI: 10.1016/j.jsbmb.2005.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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