Article
The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: a meta-analysis.
Biological psychiatry - 1 May 2005
López León Sandra, Croes Esther A, Sayed-Tabatabaei Fakhredin A, Claes Stephan, Van Broeckhoven Christine, van Duijn Cornelia M
Abstract excerpt
BACKGROUND: We conducted a meta-analysis to re-evaluate the role of the dopamine D4 receptor gene 48-base-pair- repeat (DRD4) polymorphism in mood disorders. METHODS: DRD4 allele frequencies were compared between 917 patients with unipolar (UP) or bipolar affective disorder (BP) and 1164 control subjects from 12 samples, using the Cochrane Review Manager. RESULTS: An association was found between all mood...
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