Article
Dopamine D2, D3 and D4 receptor and transporter gene polymorphisms and mood disorders.
Journal of affective disorders - 9 Sept 1996
Manki H, Kanba S, Muramatsu T, Higuchi S, Suzuki E, Matsushita S, Ono Y, Chiba H, Shintani F, Nakamura M, Yagi G, Asai M
Abstract excerpt
Disturbances in dopaminergic systems have been implicated in the etiology of mood disorders. Although genetic factors also play an important role, no major gene has been identified. We conducted an association study using the dopamine D2, D3 and D4 receptor, and transporter gene polymorphisms, co...
Topics
- Adult
- Aged
- Alleles
- Bipolar Disorder
- Carrier Proteins
- Depressive Disorder
- Dopamine Plasma Membrane Transport Proteins
- Female
- Genotype
- Humans
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Middle Aged
- Nerve Tissue Proteins
