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Article

Dopamine receptor D4 gene is associated with delusional symptomatology in mood disorders.

Psychiatry research - 17 Aug 1998

Serretti A, Macciardi F, Cusin C, Lattuada E, Lilli R, Smeraldi E

Abstract excerpt

Disturbances of the dopaminergic neurotransmitter system have been implicated in the pathogenesis of depressive symptoms. Many studies have, however, failed to detect any association between genetic markers for the dopamine system and mood disorders. A possible reason for this may lie in the definition of phenotype, which is traditionally based on psychiatric diagnosis. In this study, we investigated the...

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Source

Identifiers

PMID: 9754691
DOI: 10.1016/s0165-1781(98)00056-0

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Dopamine receptor D4 gene is associated with delusional symptomatology in mood disorders.PMID 9754691Read ↗

Genetic variants of dopamine receptor D4 and psychopathology.Semantic proximity Read ↗

No interaction between serotonin transporter gene and dopamine receptor D4 gene in symptomatology of major psychoses.Semantic proximity Read ↗

Distribution of a novel mutation in the first exon of the human dopamine D4 receptor gene in psychotic patients.Semantic proximity Read ↗

Dopamine receptor D4 gene is not associated with major psychoses.Semantic proximity Read ↗

DRD4 exon 3 variants are not associated with symptomatology of major psychoses in a German population.Semantic proximity Read ↗

DRD4 exon 3 variants associated with delusional symptomatology in major psychoses: a study on 2,011 affected subjects.Semantic proximity Read ↗

Dopamine D2, D3 and D4 receptor and transporter gene polymorphisms and mood disorders.Semantic proximity Read ↗

Dopamine D2 receptor gene not associated with symptomatology of mood disorders.Semantic proximity Read ↗

Expression and characterization of a dopamine D4R variant associated with delusional disorder.Semantic proximity Read ↗

Dopamine receptor D2 Ser/Cys 311 variant is associated with delusion and disorganization symptomatology in major psychoses.Semantic proximity Read ↗

Dopamine D3 receptor gene not associated with symptomatology of major psychoses.Semantic proximity Read ↗

No evidence of association between dopamine D4 receptor variants and bipolar affective disorder.Semantic proximity Read ↗

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