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Article

Relationship of serotonin transporter gene polymorphisms and haplotypes to mRNA transcription.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2005

Bradley Sarah L, Dodelzon Katerina, Sandhu Harinder K, Philibert Robert A

Abstract excerpt

The serotonin transporter (5HTT; chromosomal location 17q12) is an important regulator of serotonergic neurotransmission and is the site of action for a number of antidepressant medications. Sequence variation at a VNTR known as the 5HTTLPR, which is 1.4 kb upstream of the translation start of 5HTT, has been associated in some studies with increased vulnerability to depression, neuroticism, and autism. Support...

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Identifiers

PMID: 15858822
DOI: 10.1002/ajmg.b.30185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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