Article
Serotonin transporter (5-HTT) gene and bipolar affective disorder.
American journal of medical genetics - 7 Feb 1998
Esterling L E, Yoshikawa T, Turner G, Badner J A, Bengel D, Gershon E S, Berrettini W H, Detera-Wadleigh S D
Abstract excerpt
Interactions with antidepressants, as well as other biochemical evidence, implicate the serotonin transporter 5-HTT in the etiology of affective disorders. However, genetic studies have produced conflicting results concerning an association of 5-HTT with bipolar disorder. We examined a variable number tandem repeat in the regulatory region of this gene to investigate the possible contribution of 5-HTT to bipolar...
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