Article
Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka).
Biochemical and biophysical research communications - 7 Sept 2001
Chen H, Fernig D G, Rudland P S, Sparks A, Wilkinson M C, Barraclough R
Abstract excerpt
Experimentally elevated levels of S100A4 induce a metastatic phenotype in benign mammary tumour cells in vivo. In humans, the presence of S100A4 in breast cancer cells correlates strongly with reduced patient survival. Potential interacting binding partners for S100A4 have now been examined using...
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