Article
Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes.
Oncogene - 17 Feb 2005
Wang Guozheng, Zhang Shu, Fernig David G, Martin-Fernandez Marisa, Rudland Philip S, Barraclough Roger
Abstract excerpt
Increased levels of the homodimeric calcium-binding protein, S100A4, have been shown to cause a metastatic phenotype in at least three independent model systems of breast cancer and its presence in carcinoma cells has been shown to be associated with a reduction in the survival of patients suffering from a range of different cancers. S100A4 has been shown to interact in vitro with another member of the S100...
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