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Article

Effect of acute hyperhomocysteinemia on methylation potential of erythrocytes and on DNA methylation of lymphocytes in healthy male volunteers.

American journal of physiology. Renal physiology - 1 Oct 2005

Fux R, Kloor D, Hermes M, Röck T, Proksch B, Grenz A, Delabar U, Bücheler R, Igel S, Mörike K, Gleiter C H, Osswald H

Abstract excerpt

Homocysteine is a precursor of S-adenosylmethionine (AdoMet) and a metabolite of S-adenosylhomocysteine (AdoHcy). The ratio of AdoMet to AdoHcy, defined as the methylation potential (MP), indicates the flow of methyl groups within the cells. Chronic elevations of total homocysteine (tHcy) in plas...

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Identifiers

PMID: 15855656
DOI: 10.1152/ajprenal.00465.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15855656-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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