Article
Computer-assisted analysis of filopod formation and the role of myosin II heavy chain phosphorylation in Dictyostelium.
Journal of cell science - 15 May 2005
Heid Paul J, Geiger Jeremy, Wessels Deborah, Voss Edward, Soll David R
Abstract excerpt
To investigate the role played by filopodia in the motility and chemotaxis of amoeboid cells, a computer-assisted 3D reconstruction and motion analysis system, DIAS 4.0, has been developed. Reconstruction at short time intervals of Dictyostelium amoebae migrating in buffer or in response to chemotactic signals, revealed that the great majority of filopodia form on pseudopodia, not on the cell body; that filopodia...
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