Article
Automated characterization of cell shape changes during amoeboid motility by skeletonization.
BMC systems biology - 24 Mar 2010
Xiong Yuan, Kabacoff Cathryn, Franca-Koh Jonathan, Devreotes Peter N, Robinson Douglas N, Iglesias Pablo A
Abstract excerpt
BACKGROUND: The ability of a cell to change shape is crucial for the proper function of many cellular processes, including cell migration. One type of cell migration, referred to as amoeboid motility, involves alternating cycles of morphological expansion and retraction. Traditionally, this process has been characterized by a number of parameters providing global information about shape changes, which are...
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