Article
How a cell crawls and the role of cortical myosin II.
Eukaryotic cell - 1 Sept 2009
Soll David R, Wessels Deborah, Kuhl Spencer, Lusche Daniel F
Abstract excerpt
The movements of Dictyostelium discoideum amoebae translocating on a glass surface in the absence of chemoattractant have been reconstructed at 5-second intervals and motion analyzed by employing 3D-DIAS software. A morphometric analysis of pseudopods, the main cell body, and the uropod provides a comprehensive description of the basic motile behavior of a cell in four dimensions (4D), resulting in a list of 18...
Topics
- Animals
- Cell Movement
- Dictyostelium
- Image Processing, Computer-Assisted
- Mutation
- Myosin Heavy Chains
- Myosin Type II
- Phosphorylation
- Protein Transport
- Protozoan Proteins
