Integrins contribute to the establishment and maintenance of cell polarity in the follicular epithelium of the Drosophila ovary

Abstract excerpt

The generation of epithelial cell polarity is a key process during development. Although the induction and orientation of cell polarity by cell-cell and cell-extracellular matrix (ECM) interactions is well established, the molecular mechanisms by which signals from the ECM control cell polarity in developing epithelial tissues remain poorly understood. Here, we have used the follicular epithelium of the...

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