Article
The Drosophila AP axis is polarised by the cadherin-mediated positioning of the oocyte.
Development (Cambridge, England) - 1 Sept 1998
González-Reyes A, St Johnston D
Abstract excerpt
The anterior-posterior axis of Drosophila originates from two symmetry-breaking steps during early oogenesis. First, one of the two pro-oocytes within the cyst of 16 germline cells is selected to become the oocyte. This cell then comes to lie posterior to the other germline cells of the cyst, thereby defining the polarity of the axis. Here we show that the oocyte reaches the posterior of the cyst in two steps....
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