Drosophila functional elements are embedded in structurally constrained sequences.

Abstract excerpt

Modern functional genomics uncovered numerous functional elements in metazoan genomes. Nevertheless, only a small fraction of the typical non-exonic genome contains elements that code for function directly. On the other hand, a much larger fraction of the genome is associated with significant evolutionary constraints, suggesting that much of the non-exonic genome is weakly functional. Here we show that in flies,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Conserved Sequence
• Share to Drosophila
• Share to Evolution, Molecular