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Article

Population genomics: whole-genome analysis of polymorphism and divergence in Drosophila simulans.

PLoS biology - 6 Nov 2007

Begun David J, Holloway Alisha K, Stevens Kristian, Hillier Ladeana W, Poh Yu-Ping, Hahn Matthew W, Nista Phillip M, Jones Corbin D, Kern Andrew D, Dewey Colin N, Pachter Lior, Myers Eugene, Langley Charles H

Abstract excerpt

The population genetic perspective is that the processes shaping genomic variation can be revealed only through simultaneous investigation of sequence polymorphism and divergence within and between closely related species. Here we present a population genetic analysis of Drosophila simulans based on whole-genome shotgun sequencing of multiple inbred lines and comparison of the resulting data to genome assemblies...

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PMID: 17988176
DOI: 10.1371/journal.pbio.0050310
PMCID: PMC2062478

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