Article
Biosynthesis of glyoxylate from glycine in Saccharomyces cerevisiae.
FEMS yeast research - 1 May 2005
Villas-Bôas Silas Granato, Kesson Mats, Nielsen Jens
Abstract excerpt
Glyoxylate biosynthesis in Saccharomyces cerevisiae is traditionally mainly ascribed to the reaction catalyzed by isocitrate lyase (Icl), which converts isocitrate to glyoxylate and succinate. However, Icl is generally reported to be repressed by glucose and yet glyoxylate is detected at high levels in S. cerevisiae extracts during cultivation on glucose. In bacteria there is an alternative pathway for glyoxylate...
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