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Article

Metabolic phenotype of phosphoglucose isomerase mutants of Corynebacterium glutamicum.

Journal of biotechnology - 4 Sept 2003

Marx Achim, Hans Stephan, Möckel Bettina, Bathe Brigitte, de Graaf Albert A, McCormack Ashling C, Stapleton Cliona, Burke Kevin, O'Donohue Michael, Dunican L K

Abstract excerpt

A series of experiments reported in the literature using fluxomics as an efficient functional genomics tool revealed that the L-lysine production of the Corynebacterium glutamicum strain MH20-22B correlates with the extent of intracellular NADPH supply. Some alternative metabolic engineering strategies to increase intracellular NADPH supply in the C. glutamicum strain DSM5715 were considered and finally the...

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Identifiers

PMID: 12948638
DOI: 10.1016/s0168-1656(03)00153-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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